NeuroScience Inc. Calm G
Contains a blend of ingredients important for regulating glutamate activity, stress-reduction, metabolic health, and mitochondrial function.
N-acetyl-L-cysteine: Precursor to L-cysteine (1). L-cysteine is required for the synthesis of glutathione, an endogenous antioxidant important for mediating oxidative stress (2).
L-theanine: Amino acid that acts as a glutamate receptor antagonist (3).* Glutamatergic signaling underlies mechanisms related to anxiousness and stress (4). In a double-blind, placebo-controlled study, L-theanine was shown to significantly reduce stress (5).*
Alpha-lipoic acid: Antioxidant that is able to regenerate endogenous antioxidants and scavenge metal ions and free radicals (6).* Evidence suggests the insulin-signaling pathway is sensitive to redox status (6). Alpha-lipoic acid can influence the redox status in cells important for the translocation of glucose transporters and increasing glucose uptake (6).*
Coenzyme Q10: Compound found in nearly every human cell that is essential for mitochondrial function and antioxidant protection (7).*
- Rushworth G and Megson I. Pharmacol Ther. 2014;141(2):150-9.
- Schmitt B, et al. Redox Biol. 2015;6:198-205.
- Kakuda T, et al. Biosci Biotechnol Biochem. 2002;66(12):2683-6.
- Bermudo-Soriano C, et al. Pharmacol Biochem Behav. 2012;100(4):752-74.
- Kimura K, et al. Biol Psychol. 2007;74(1):39-45.
- Rochette L, et al. Can J Physiol Pharmacol. 2015;93(12):1021-7.
- Garrido-Maraver J, et al. Front Biosci (Landmark Ed). 2014;19:619-33.
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